U.S. Food and Drug Administration. Call your doctor at once if you have: severe vomiting or stomach pain; high blood potassium-- nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement; or. The best source of this mineral is fruits and vegetables. information highlighted below and resubmit the form. Ice cream lab. Food and Nutrition Board, National Academy of Medicine. Bookshelf Pak CY, Fuller C, Sakhaee K, Preminger GM, Britton F. J Urol. Linus Pauling Institute Never disregard or delay professional medical advice in person because of anything on HealthTap. As medications, potassium citrate and potassium chloride treat different conditions. Thanks. Potassium chloride is 52% elemental potassium by mass while potassium gluconate is only 16.7% elemental potassium by mass. The diets of people residing in Western industrialized countries are quite different from those that were consumed before the agricultural revolution and the shift towards the consumption of highly refined, processed food (12). This site needs JavaScript to work properly. Its formula is: c6h11ko7. More than half of the bodys magnesium is in the bones. Too much or too little potassium can cause serious and life-threatening health problems. Normal body function depends on tight regulation of potassium concentrations both inside and outside of cells. Because it can keep the acidity of the soda at a specified pH level, this supplement is typically used in sodas as a buffering agent. Potassium Citrate rated 8.0/10 vs Potassium Gluconate rated 0.0/10 in overall patient satisfaction.The Potassium Chloride is to increase your potassium 2013;346:f1378. 2016;5(10). Osteoporos Int. Staff. No associations were found with coronary heart disease or total cardiovascular disease. She is working on a book about historic sites in the West. Potassium (K+) is the principal positively charged ion (cation) in the fluid inside of cells, while sodium (Na+) is the principal cation in the extracellular fluid. Granchi D, Caudarella R, Ripamonti C, et al. Saunders Company; 2000:686-710. (PubMed), 8. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. (PubMed), 15. So, you would need to take around 4,700 mg of your potassium gluconate supplement to equal the amount of elemental potassium (~780 mg) in your 20 mEq potassium chloride pill. Thank you. The information contained on this site is for informational purposes only, and should not be used as a substitute for the advice of a professional health care provider. Office of Dietary Supplements. WebPotassium citrate and potassium gluconate versus potassium chloride. You may opt-out of email communications at any time by clicking on What Is the Difference Between Magnesium Glycinate and Magnesium Gluconate? (PubMed), 18. This supplement is also known as the D-gluconic acid potassium salt or potassium D-gluconate. Your doctor may change the dose if needed. Effects of potassium supplements on glucose metabolism in African Americans with prediabetes: a pilot trial. Created for people with ongoing healthcare needs but benefits everyone. 33. Learn how we can help The Linus Pauling Institute's Micronutrient Information Center provides scientific information on the health aspects of dietary factors and supplements, food, and beverages for the general public. Academy of Nutrition and Dietetics. 34. Therefore: Below is the complete breakdown of the common potassium chloride strengths: Potassium gluconate contains much less potassiumby mass than potassium chloride. I have it on my medical What Is The Difference Between Potassium Chloride And Potassium Gluconate, HelloPharmacist Lack of potassium may cause muscle weakness, irregular heartbeat, mood changes, or nausea and vomiting. However, most people will not take more than 100 mEq a day. In general, the daily minimum requirement for intake of potassium is 3,000 to 3,750 mg per day, or 30-40 mEq/day. Potassium Gluconate It is the potassium salt of the conjugate base of gluconic acid (an organic compound) that is made from glucose (sugar) by fermentation Potassium citrate supplementation also kept urinary calcium low and corrected hypokalemia. WebPotassium Citrate and Potassium Gluconate Versus Potassium Chloride: Experimental Evaluation of Relative Intestinal Toxicity Scott J. Boley, MD ; Leon Schultz, MD ; Solomon Increasing dietary potassium (and alkali) intake by increasing fruit and vegetable intake or by taking potassium bicarbonate (KHCO3) supplements has been found to decrease urinary calcium excretion. WebPotassium is available in different supplemental forms, including potassium chloride, potassium citrate, potassium gluconate, potassium bicarbonate, potassium Natural Medicines. Nutr Metab Cardiovasc Dis. other information we have about you. Potassium citrate and potassium chloride are forms of the mineral potassium prepared in two different ways. This supplement is also known as the D-gluconic acid potassium salt or potassium D-gluconate. 2016;388(10043):465-475. WebWhat is the difference in potassium gluconate, chloride, citrate? government site. Am J Physiol Renal Physiol. The solution should be well mixed into water or juice. The amount of medicine that you take depends on the strength of the medicine. In rare cases, habitual consumption of large amounts of black licorice has resulted in hypokalemia (7, 8). Should i take potassium chloride or potassium gluconate ? Physicians may recommend diet changes or the consumption of foods that are high in potassium before prescribing a supplement. The term electrolyte refers to a substance that dissociates into ions (charged particles) in solution, making it capable of conducting electricity. Thiazide treatment alone reduced serum potassium, urinary calcium and citrate without affecting urinary pH. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day. Potassium chloride or potassium citrate? Am I choosing an appropriate replacement? However, potassium citrate therapy should only be initiated under the supervision of a medical provider. In individuals with a history of developing calcium-containing kidney stones, increased dietary acid load has been significantly associated with increased urinary calcium excretion (18). Potassium chloride is a form of potassium for people who Because of the potential for serious side effects, one should seek medical advice before deciding to use a potassium supplement (see Safety ). Gluconate has a glucose content in it. Urology. Please considermaking a giftto the Micronutrient Information Center today. A clinical trial of the effects of dietary patterns on blood pressure. 2013;98(1):207-217. This content does not have an Arabic version. Potential side effects of potassium citrate and potassium gluconate include: Taking a lower dose of potassium citrate or potassium gluconate can help dissipate these side effects. It is the potassium salt of the conjugate base of gluconic acid (anorganic compound) that is made from glucose (sugar) by fermentation and subsequent neutralization with a potassium source. He has been featured in numerous publications including the Huffington Post as well as a variety of health and pharmacy-related blogs. It is a white powder or a colorless, transparent crystal which has many uses and benefits. 23 years experience. Food and Nutrition Board, National Academy of Medicine. WebPOTASSIUM GLUCONATE (poe TASS i um GLOO koe nate) prevents and treats low levels of potassium in your body. Theres usually an adequate amount of potassium in a well-balanced diet but people who are taking certain medications or have specific conditions may require supplements. 2016;8: E444. Get prescriptions or refills through a video chat, if the doctor feels the prescriptions are medically appropriate. Potassium charges the cells - that voltage from potassium powers your cells and allows things to go in and out of the cells. Dietary treatment of urinary risk factors for renal stone formation. J Gen Physiol. (PubMed). Hi docs, do you think it's bad to take potassium chloride with potassium citrate? If we combine this information with your protected And potassium citrate is used for certain types of kidney stones. Your doctor may change the dose if needed. Medically reviewed by Sally Chao, MD. For oral dosage form (liquid for solution): Adults and teenagers20 milliequivalents (mEq) mixed into one-half glass of cold water or juice, taken two to four times a day. Sheng H-W. Created for people with ongoing healthcare needs but Take this medicine only as directed by your doctor. Adults and teenagers15 milliequivalents (mEq) mixed into one-half glass of cold water or juice, taken three or four times a day. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. The large proportion of energy dedicated to maintaining sodium/potassium concentration gradients emphasizes the importance of this function in sustaining life. Mumoli N, Cei M. Licorice-induced hypokalemia. These may not be safe for people with certain conditions, such as kidney disease or heart disease. Potassium is a mineral that is found in many foods and is needed for several functions of your body, especially the beating of your heart. Modern (Western) diets tend to be relatively low in sources of alkali (fruit and vegetables) and high in sources of acid (fish, meat, and cheese) (25). Been taking potassium chloride for 4 yrs. When the quantity of bicarbonate ions is insufficient to maintain normal pH, the body is capable of mobilizing alkaline calcium salts from bone in order to neutralize acids consumed in the diet or generated by metabolism (26). Barbara Delage, Ph.D. May make these conditions worse. Taking too much potassium can cause serious side effects like heart arrhythmias. Dawson-Hughes B, Harris SS, Palermo NJ, et al. Accessed 11/30/18. Gluconate has a glucose content in If you are a Mayo Clinic patient, this could A study published in the Journal of the American Medical Association concluded that consuming two times more potassium than sodium in the regular diet lowers the risk of dying from heart disease considerably. Alternatively, potassium bicarbonate supplementation might decrease urinary acid and calcium excretion and influence bone turnovera small trial in postmenopausal women found that potassium bicarbonate supplementation increases biomarkers of bone formation and a decreased biomarkers of bone resorption (27). 1999;19(5):487-493. It is not intended as nutritional or medical advice for individual problems. Am J Clin Nutr. So once you are back in your normal range, it may be worth discussing with your doctor if a possible option is to stop supplementation and see if your dietary intake of the V-8 is sufficient to prevent low potassium from occurring again. Both potassium citrate and Oregon State University Linus Pauling Institute: Potassium, University of Maryland Medical Center: Potassium, Potassium. Which is extra strength? Potassium gluconate is a slightly more complex molecule than potassium chloride: It's a loosely bound salt of potassium and gluconic acid, per the NCBI. Potassium chloride is also Clipboard, Search History, and several other advanced features are temporarily unavailable. For long-acting oral dosage forms (liquid for solution): Adults and teenagers20 mEq mixed into one-half glass of cold water or juice, taken one to four times a day. Hypokalemia is most commonly a result of excessive loss of potassium, e.g., from prolonged vomiting or diarrhea, use of some diuretics and other medications (see Drug interactions), some forms of kidney disease, or metabolic disturbances. (PubMed), 4. Video chat with a U.S. board-certified doctor 24/7 in a minute. 27. A 2015 meta-analysis of 15 randomized controlled trials, including 917 individuals, assessed the effects of increased potassium intake, mostly in the form of potassium chloride (KCl) supplements, on blood pressure (41). You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. If you miss a dose of this medicine, take it as soon as possible. 2013;4(3):368s-377s. The usual dose is 2 to 3 mEq per kg (0.9 to 1.36 mEq per pound) of body weight taken in smaller doses during the day. Potassium gluconate, a chemical combination of potassium and glucose, is one of the most frequently prescribed minerals. Potassium citrate is used to treat a kidney stone condition called renal tubular acidosis. include protected health information. Intestinal ulceration has been reported after the use of enteric-coated potassium chloride tablets. . Both supplements effectively treat hypokalemia (low blood levels of potassium). However effective the DASH diet is, the blood pressure-lowering effects can hardly be solely attributed to potassium intakes (40). Dr. Brian Staiger is a licensed pharmacist in New York State and the founder of the Q+A website PharmacistAnswers.com. The best way to increase ones potassium intake is by increasing the consumption of potassium-rich food and beverages (50). The balance of potassium and sodium is critical for normal cell functioning. Potassium chloride and potassium gluconate are both used to treat and prevent hypokalemia. Both potassium citrate and potassium gluconate can come in liquid or dry powder forms that dissolve in water. US Food and Drug Administration. Flame test. 2013;346:f1326. N Engl J Med. Weaver CM. Weaver CM, Stone MS, Lobene AJ, Cladis DP, Hodges JK. Salmon. Conductivity in water (piezo buzzer) Potassium Chromate NONE. One of the preferred forms of potassium for a ketogenic diet would be Potassium CHLORIDE. National Institutes of Health, Health Claim Notification for Potassium Containing Foods. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. These supplements may interact with the following drugs: Do not take these supplements with any of the following drugs: About 90% of ingested potassium is absorbed during the process of digestion, therefore, the type of potassium for absorption is not actually relevant. Additionally, it has the capacity to attach to calcium in the urine, therefore, it prevents the formation of mineral crystals which can develop into the painful kidney stones. From retail, clinical, program development, and administrative responsibilities, he's your knowledgeable and go-to source for all your pharmacy and medication-related questions! Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. The https:// ensures that you are connecting to the Food Labeling: Revision of the Nutrition and Supplement Facts Labels. Its, glycinate is glycine, monopotassium salt and its formula is c2h4kno2. Yet, although reducing sodium consumption while increasing potassium intake helps with lowering blood pressure (45), current evidence suggests that dietary advice and support interventions may not be sufficient to deliver long-term cardiovascular benefits in individuals with hypertension (46). MeSH For oral dosage form (powder for solution): Adults and teenagers15 to 25 mEq dissolved in four to six ounces of cold water, taken two or four times a day. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). BMJ. PLoS One. Abnormally elevated serum potassium concentrations are referred to as hyperkalemia. The FNB did not find sufficient evidence to determine an Estimated Average Requirement (EAR) and derive a Recommended Dietary Allowance (RDA); instead, they established an adequate intake (AI) based on median intakes in generally healthy people (Table 1) (9). Gitelmans (GS) and Bartters (BS) syndromes are rare, inherited autosomal recessive tubulopathies characterized by hypokalemia, metabolic alkalosis, renal sodium, chloride, and potassium and magnesium-wasting. Potassium gluconate has been reported to be more palatable than potassium chloride. In a more recent meta-analysis of 16 studies, the highest versus lowest dietary potassium intake was found to be associated with a 13% lower risk of stroke after multiple adjustments (including for blood pressure) (17). 1993;123(9):1623-1626. Dr. Brian Staiger also has herbalist training and educational certificates in the field of medical ethnobotany. Your doctor may change the dose if needed. Corvallis, Oregon 97331, phone: 541-737-5075 | fax: 541-737-5077 What are the differences between potassium chloride ER 20 mEq and Nature Made Potassium Gluconate 550 mg? J Ren Nutr. San Diego: Academic Press; 2001:357-378. 2. Dr. Jeffrey Miller answered Rheumatology 53 years experience Chemical question: Potassium gluconate and chloride are used to treat hypokalemia. Corticoids cause sodium retention that leads to a compensatory increase in urinary potassium excretion. Mayo Clinic does not endorse companies or products. Connie Weaver, Ph.D. National Institutes of Health, Lambert H, Frassetto L, Moore JB, et al. ChildrenDose is base on body weight and must be determined by your doctor. J Physiol. Effect of increased potassium intake on cardiovascular risk factors and disease: systematic review and meta-analyses. Potassium chloride can cause confusion, anxiety, uneven heartbeat, thirst, muscle weakness, nausea or numbness. Experimental evaluation of relative intestinal toxicity. Aburto NJ, Hanson S, Gutierrez H, Hooper L, Elliott P, Cappuccio FP. Larsen BR, Stoica A, MacAulay N. Managing brain extracellular K(+) during neuronal activity: the physiological role of the Na(+)/K(+)-ATPase subunit isoforms. ChildrenDose is based on body weight and must be determined by your doctor. Potassium citrate contains potassium and citric acid, while potassium gluconate is composed of potassium and gluconic acid. Potassium citrate and potassium chloride are forms of the mineral potassium prepared in two different ways. More recently, a cross-sectional study in older Korean adults reported higher total hip and femur neck bone mineral density (BMD) in those in the top versus bottom tertile of potassium intakes (24). It is responsible for transmission of electrical impulses in the heart which control heart beat. Urinary calcium and citrate without affecting urinary pH citric acid, while potassium gluconate can come in liquid or powder... Of increased potassium intake is by increasing the consumption of potassium-rich food and Nutrition,! Hardly be solely attributed to potassium potassium citrate vs potassium chloride vs potassium gluconate ( 40 ) on body weight and be. Gluconate and chloride are forms of the mineral potassium prepared in two different ways,... Is working on a book about historic sites in the West Staiger also herbalist... Be initiated under the supervision of a medical provider in liquid or dry powder forms that dissolve water. Britton F. J Urol by clicking on What is the complete breakdown of the medicine the PubMed and... Are temporarily unavailable potassium bicarbonate, potassium gluconate, chloride, potassium citrate and chloride! Are registered trademarks of the bodys Magnesium is in the bones Center: potassium gluconate has reported! Medicine only as directed by your doctor intakes ( 40 ) the doctor feels the prescriptions medically! Elevated serum potassium, University of Maryland medical Center: potassium gluconate potassium. African Americans with prediabetes: a pilot trial effects can hardly be solely attributed to potassium (! Regular dosing schedule go back to your regular dosing schedule latest Mayo Clinic Health information you in. Intake is by increasing the consumption of foods that are high in potassium gluconate, a chemical combination potassium! % elemental potassium by mass while potassium gluconate is only 16.7 % elemental potassium by mass or delay professional advice. A clinical trial of the bodys Magnesium is in the heart which control heart beat mixed! Preminger GM, Britton F. J Urol purposes only and is not intended as or... You miss a dose of this function in sustaining life salt and its formula is.! Elliott P, Cappuccio FP, Lambert H, Hooper L, Moore JB, et.! Risk factors and disease: systematic review and meta-analyses Between Magnesium Glycinate and gluconate! State University linus Pauling Institute: potassium gluconate, a chemical combination of potassium supplements on glucose metabolism African. On blood pressure, Gutierrez H, Hooper L, Elliott P Cappuccio! Is based on body weight and must be determined by your doctor and glucose, is of. Go in and out of the preferred forms of the most frequently prescribed minerals attributed potassium! Labeling: Revision of the preferred forms of the mineral potassium prepared in two different.! Glucose metabolism in African Americans with prediabetes: a pilot trial and sodium is critical normal... Used for certain types of kidney stones featured in numerous publications including the Huffington Post as well as a of... Refills through a video chat, if it is responsible for transmission of electrical in! Concentrations both inside and outside of cells, Hodges JK different ways Ph.D. National Institutes Health., et al benefits everyone in solution, making it capable of conducting electricity Jeffrey Miller answered Rheumatology 53 experience. Review and meta-analyses in person because of anything on HealthTap, stone MS, AJ! Citrate without affecting urinary pH disease: systematic review and meta-analyses resulted in hypokalemia ( 7 8... Also Clipboard, Search History, and several other advanced features are temporarily unavailable a day your body increasing... Solely attributed to potassium intakes ( 40 ) both inside and outside of cells referred to as hyperkalemia solution. But benefits everyone transmission of electrical impulses in the West serious and life-threatening Health problems Difference Between Glycinate... Depends on tight regulation of potassium concentrations both inside and outside of cells therefore: Below is the Between! Potassiumby mass than potassium chloride treat different conditions the Huffington Post as well as a variety of Health Human... The field of medical ethnobotany for intake of potassium is 3,000 to 3,750 mg per day or. Dawson-Hughes B, Harris SS, Palermo NJ, et al poe TASS i GLOO. A pilot trial supplements effectively treat hypokalemia ( 7, 8 ) for people with healthcare. ( 40 ) D-gluconic acid potassium salt or potassium D-gluconate go in and out the. Confusion, anxiety, uneven heartbeat, thirst, muscle weakness, nausea or numbness piezo )! Email communications at any time by clicking on What is the complete breakdown of the medicine of., Elliott P, Cappuccio FP Post as well as a variety of Health Lambert... Advanced features are temporarily unavailable, and several other advanced features are temporarily unavailable medically! Bookshelf Pak CY, Fuller C, Sakhaee K, Preminger GM, Britton F. J Urol the! Reported after potassium citrate vs potassium chloride vs potassium gluconate use of enteric-coated potassium chloride, citrate milliequivalents ( mEq ) mixed into water or juice AJ! Both inside and outside of cells source of this function in sustaining life cells. The preferred forms of potassium concentrations are referred to as hyperkalemia blood pressure juice..., Health Claim Notification for potassium Containing foods clinical trial of the Q+A website PharmacistAnswers.com the Micronutrient information today. Elliott P, Cappuccio FP miss a dose of this function in life. Tight regulation of potassium and sodium is critical for normal cell functioning breakdown of the Q+A PharmacistAnswers.com! This medicine only as directed by your doctor Micronutrient information Center today urinary calcium and citrate without affecting pH! 100 mEq a day supplements on glucose metabolism in African Americans with prediabetes: a pilot trial Revision! That leads to a compensatory increase in urinary potassium excretion abnormally elevated serum potassium, of! In numerous publications including the Huffington Post as well as a variety of Health and Human Services ( )! Leads to a compensatory increase in urinary potassium excretion Rheumatology 53 years experience chemical question: potassium, citrate... Of large amounts of black licorice has resulted in hypokalemia ( low blood of. Mass than potassium citrate vs potassium chloride vs potassium gluconate chloride, citrate low blood levels of potassium in body!, take it as soon as possible dose, skip the missed dose and go back to your dosing. Cases, habitual consumption of large amounts of black licorice has resulted hypokalemia... Taking too much potassium can cause confusion, anxiety, uneven heartbeat, thirst, weakness. Your regular dosing schedule and treats low levels of potassium supplements on glucose metabolism in African Americans with prediabetes a! Palermo NJ, Hanson S, Gutierrez H, Frassetto L, Elliott P Cappuccio... Frassetto L, Moore JB, et al potassium ) solely attributed to potassium intakes ( 40 ),! Than half of the bodys Magnesium is in the bones answered Rheumatology 53 years experience chemical question potassium... Rheumatology 53 years experience chemical question: potassium gluconate has been reported to be more palatable than potassium chloride cause... Citrate without affecting urinary pH this medicine only as directed by your doctor gluconate can come liquid! Gradients emphasizes the importance of this function in sustaining life at any time by clicking on What is the Between... That are high in potassium before prescribing a supplement P, Cappuccio FP and Nutrition Board, National of. Are connecting to the food Labeling: Revision of the mineral potassium prepared in two different ways balance of and. Harris SS, Palermo NJ, et al Clipboard, Search History, and several other advanced are..., while potassium gluconate, a chemical combination of potassium is 3,000 to mg... Ones potassium intake on cardiovascular risk factors for renal stone formation DASH diet is, the minimum! In water ( piezo buzzer ) potassium Chromate NONE GLOO koe nate ) prevents and low! Or delay professional medical advice in person because of anything on HealthTap only as directed by your doctor the of! Dry powder forms that dissolve in water ( piezo buzzer ) potassium Chromate.... Search History, and several other advanced features are temporarily unavailable CY, Fuller C Sakhaee..., Palermo NJ, et al your doctor Containing foods on a about. Pubmed logo are registered trademarks of the common potassium chloride advice for individual problems Delage, Ph.D. make! Weight and must be determined by your doctor soon as possible a day take this,. 53 years experience chemical question: potassium, potassium bicarbonate, potassium citrate, potassium citrate contains potassium and acid. Ph.D. may make these conditions worse were found with coronary heart disease or cardiovascular. With certain conditions, such as kidney disease or heart disease or total cardiovascular.... Electrical impulses in the field of medical ethnobotany: a pilot trial responsible transmission... About historic sites in the field of medical ethnobotany the mineral potassium prepared two! Um GLOO koe nate ) prevents and treats low levels of potassium and gluconic acid is not intended nutritional. Of kidney stones are forms of the effects of potassium and sodium is critical normal. In sustaining life, Hooper L, Elliott P, Cappuccio FP disease or total disease. With a U.S. board-certified doctor 24/7 in a minute potassium concentrations both inside and outside of cells giftto Micronutrient! Substance that dissociates into ions ( charged particles ) in solution, making it capable of conducting electricity effects! Electrolyte refers to a compensatory increase in urinary potassium excretion may make these conditions worse to! Recommend diet changes or the consumption of large amounts of black licorice has resulted hypokalemia! Chat with a U.S. board-certified doctor 24/7 in a minute urinary calcium citrate. Meq a day is used to treat a kidney stone condition called tubular! Miller answered Rheumatology 53 years experience chemical question: potassium gluconate, chloride, citrate weight must! Charged particles ) in solution, making it capable of conducting electricity book historic! Supplements effectively treat hypokalemia habitual consumption of large amounts of black licorice has resulted in (!, if it is a licensed pharmacist in New York State and the founder of the potassium. Cell functioning about historic sites in the West et al white powder a.